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Retinal intelligence for whole-body risk

A standard eye scan, read as an early signal of systemic risk.

PRiSM turns retinal imaging that clinics already capture into an interpretable read on a patient's risk of vascular events — so care teams can find and prioritize the right patients sooner.

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The invention

Risk you can see and explain — not an opaque score.

PRiSM turns a standard eye scan into an early signal of whole-body risk, flagging elevated risk of developing systemic vascular disease — heart attack, stroke, and kidney failure — earlier, so clinicians can act sooner. Rather than a black-box number, PRiSM registers fundus, OCT, angiography, and OCTA into a single map of the eye and reads interpretable vascular and structural features from it.

The method behind it
Patent-pending: PRiSM cross-correlates retinal features before the model runs, separates patients who share the same ocular grade but differ in systemic risk, and fuses imaging with each patient's clinical context to build a personalized risk picture.
How it works

Four steps, one shared model of the retina.

01

Capture

Fundus, OCT, angiography, and OCTA images from standard clinical devices — plus the health record.

02

Unify

Images are aligned into one shared model of the retina.

03

Interpret

Interpretable vascular and structural features, checked against clinical knowledge.

04

Stratify

Retinal signals are fused with patient context into personalized risk — and clear next steps.

Runs on the retinal cameras and scanners clinics already own.
Why it compounds

A proprietary data flywheel.

The four steps run once per patient. The flywheel runs continuously across all of them — every new scan or EHR update sharpens the model and keeps each patient's risk profile current, and that advantage compounds as more clinics come online.

  • 1More scans and records — each partner clinic contributes retinal imaging and health-record data already captured in routine care.
  • 2A sharper model — more paired imaging, records, and outcomes refine how PRiSM reads risk.
  • 3Better risk reads — sharper stratification means more clinical value per scan.
  • 4More partners — that value draws new clinics and networks, feeding the loop again.
DATA FLYWHEEL Scans + EHR Sharper model Better risk reads More partners
Why this matters

Reach the right patients sooner.

Systemic disease often shows in the retina before a patient feels it. When that signal goes unused, high-risk patients get the same follow-up as everyone else. PRiSM turns retinal data your teams already collect into a way to find and prioritize those patients.

For clinicians and care teams

  • Spot high-risk patients earlier, inside routine retinal workflows.
  • Tell apart patients who share an ocular grade but differ in systemic risk.
  • See the retinal and patient factors behind each risk read.
  • Prioritize follow-up, monitoring, and referrals with clear next steps.

For health systems and population health

  • Flag high-risk cohorts across a clinic, network, or covered population.
  • Target early, wellness-oriented interventions where they matter most.
  • Coordinate care around patients trending toward systemic events.
  • Work from retinal data already captured in everyday visits.
Partnership opportunities

Built to fit the care you already deliver.

PRiSM is designed to integrate with clinical imaging, health records, and care programs. We welcome the right partners to build and scale with us.

Retinal imaging device makers
Electronic health record and health IT platforms
Health systems and provider networks
Payers and value-based care organizations
Primary care and teleophthalmology programs
Pharmaceutical and clinical research partners

See what PRiSM reads in a routine eye scan.

We're partnering with a focused set of clinics, health systems, and research collaborators. Request a briefing to see the approach and the data behind it.

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